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Senior Principal Scientist/General Manager DMPK

Mumbai, MH
Job Code:
  • Biotechnology & Science
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Job Details

To lead the characterization of drug metabolism and pharmacokinetic properties of new chemical entities in discovery and development.To plan activities to screen, select, optimize and develop novel drug molecules in preclinical and clinical studies. To provide metabolite Identification support for pre-clinical and clinical studies for NCEsTo manage the operations of the internal team and to oversee conduct of studies at external CROs (bio-analytical method development, validation, sample analysis) to ensure timely delivery of quality data to advance moleculesTo plan and monitor the required studies in accordance with the project requirements and communicate the data to the internal stakeholders.The position requires inter-disciplinary collaboration with pharmacology, toxicology and clinical sciences in understanding exposure-efficacy and exposure-toxicity relationships and dose selection for clinical studies. Provide DMPK screening and assist in candidate selection, metabolite Identification support to chemical research for structural optimization at early drug discoveryProvide metabolism packages, metabolite structure elucidation and coverage to late stage clinical candidates to support regulatory filingsProvide bioanalytical support for clinical supporting toxicology and clinical studies and interpretation of PK/TK dataProvide summary data and presentations to cross functional teams and represent DMPK in internal and external meetingsBuild a strong team with scientific capability to ensure that the organization is able to manage its expanding portfolio of programs and innovative products across various stages of clinical development using modeling and simulation approaches and clinical pharmacology support.
Additional Degree: BA (Arts) | B.Com. (Commerce) | B.Pharm. (Pharmacy) | B.Plan. (Planning) | B.Sc. (Science) | BBA/ BBM/ BBS | BCA (Computer Application) | Diploma-Other Diploma | B.Ed. (Education) | BHM (Hotel Management)

Experience: 7-12


Chemical Research | Clinical Research | Drug Regulation
Applying for this job will take you to an external site


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